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While the corona virus epidemic, which is the fearful dream of people in many countries of the world, continues to kill rapidly, many invasive and non-invasive treatments are applied according to the severity of the cases. Many recommendations are being announced by infection specialists and public health experts in order not to be infected, and the political will puts restrictions and precautions covering the whole country into practice. This virus epidemic, which causes serious health and economic problems, also creates difficulties in the context of treatment. From a practical point of view, either every individual will get this infection or the masses will be able to get rid of this scourge by immunizing when a vaccine is found. Unfortunately, a fully effective application for the treatment of COVID-19, which spreads very aggressively, has not been implemented.
Conventional treatments: Research has begun on multiple pharmaceutical drugs such as hydroxychloroquine (anti-malarial drug), alone or in combination with azithromycin (an antibiotic), remdesivir (anti-viral), and ivermectin (anti-parasitic). Among clinical pharmaceutical studies, hydroxychloroquine with a combination of azithromycin appears to be the most effective so far in reducing the COVID-19 viral load. Despite the use of these drugs, patients with severe symptoms continue to have respiratory failure. Therefore, there is still an established belief that something is missing. It is a pity that the researches are completely focused on the help of the pharmaceutical industry. It is necessary to consider the patient's condition, human and cellular physiology, and other avenues and holistic approaches to provocation of recovery. Looking back, we realize that treating the patient was much more important than just treating the virus. In this context, when we begin to evaluate and optimize cellular and mitochondrial function, we begin to use the body's own army and its healing capacity against this virus. As we look at potential options for the treatment of cellular dysfunction resulting from COVID-19, it would be wise to consider one of the most naturally occurring substances in the universe, oxygen and ozone, as a treatment.
While palliative treatment, supportive treatment and quarantine practices are carried out for those with positive tests, unfortunately, patients with respiratory distress and whose fever cannot be controlled are unfortunately taken to intensive care units. In intensive care follow-ups, respiratory support is provided by intubation, if necessary, depending on the severity of the disease. In even more severe cases, very costly treatments such as oxygenation of the blood by taking it out of the body (ECMO) and supports are offered to the patients. In fact, forced oxygen to COVID-19 patients who cannot use oxygen due to mitochondria damage in the case of artificial ventilation (connecting to a ventilator) in the intensive care unit increases the production of ROS from harmful oxygen wastes (free radicals: ROS) to the body and causes more damage to the mitochondria. Most of these patients already have reduced oxygen utilization capacity as a result of the infection itself, along with mitochondria, excessive production of free radicals and ROS. When we try to force oxygen into lung tissue, we create a state of hyperoxygenation (too much oxygen). Hyperoxygenation creates oxygen toxicity by stimulating the production of more free radicals, which destroy more mitochondria faster, exacerbating oxidative stress. If we give more than 50% oxygen to the lungs for a long time with the Hatat ventilator, we will dry the lungs and prepare the ground for fibrosis.
The side of this disease that puts people in a difficult situation is the emergence of a condition called cytokine storm. Recent research shows that mitochondrial destruction and mutation occur in COVID-19.
Corona virus's favorite place is in the lung, where it binds to ACII receptors and quickly renders the lung inoperable. The damage caused by COVID-19 to the mitochondria in our cells becomes greater than the oxygen utilization capacity and energy production, creating an environment that disables mitochondrial repair and oxygen utilization. Some signs of mitochondrial damage due to lack of oxygen use are: shortness of breath, fatigue, weakness, temperature changes (cold or fever) and general body aches. Do these symptoms sound familiar to you? These symptoms are symptoms of COVID-19, but also mitochondrial oxygen use dysfunction. Clinically, these symptoms indicate the presence of mitochondrial defects that cause mitochondrial oxygenation and utilization dysfunction caused by the SARS-CoV-2 virus. As a result of cellular deterioration, leakages from capillaries, accumulation of fluid and exudate in the alveoli, disruption of gas exchange, in other words, the inability to remove carbon dioxide and not provide oxygen to the body occur.
Subsequently, heart failure, secondary infections, multi-organ failure and death may occur. Our immune system activates in a panic and activates a high amount of defense cells. However, our immune system consumes defensive weapons by using disproportionately excessive force here. During this period, especially those with weak immune systems, serious co-morbidities and the elderly are at high risk. The more ACE2 receptors that COVID-19 attacks, the greater the mitochondrial dysfunction, the less oxygen used by our cells, and the more aggressive the COVID-19 symptoms. One of the reasons chronic diseases such as insulin resistance, diabetes, cancer, heart disease, and immunocompromised patients are at higher risk for COVID-19 complications is that these patients already have an underlying mitochondrial dysfunction from their disease and medication. We are putting an additional burden on cells that are already struggling with oxidative stress.
The use of intravenous vitamin C in the treatment of COVID-19 is becoming increasingly common in various parts of the world. These antioxidants play an important auxiliary role in reducing the symptoms of COVID-19 as well as reducing cellular damage and free radicals. The fact that practical measures such as vaccines cannot be put into effect immediately becomes urgent in terms of the need for other treatment methods. We will consider ozone therapy as a cheap, practical and effective suggestion.
After the world health organization paved the way for treatment restrictions in the current situation, doctors put many different treatments into action in order to benefit patients. Positive results from ozone therapy applied during previous viral epidemics are in the position to shed light on this day. Perhaps the answer to correct mitochondrial dysfunction and improve oxygen utilization while improving COVID-19 symptoms lies in the research and integration of treatments such as intravenous ozone. Because medical ozone therapy is a powerful method to oxygenate the body without further damage to mitochondria and cells. Ozone is a natural substance consisting of 3 oxygen atoms. The use of ozone gas in treatment is called ozone therapy. In 2003, in China, Prof. Dr. Li Zelin showed that the SARS virus, which is from the same virus family as COVID, can be killed by 99.2% with ozone. Again, Dr. In his clinical studies, Wilson showed that 99% of the SARS virus could be killed by ozone therapy, supporting this data.
Another example: During the deadly EBOLA virus outbreak in Africa, Dr. Rowen went to Africa with his team at the invitation of the President of Sierra Leone, and 6 of the patients who applied ozone therapy to 6 EBOLA patients recovered without complications. Dr. Rowen is currently a very popular specialist in ozone therapy for COVID-19 patients in the United States.
In the city of Huan, where the COVID-19 epidemic broke out, the patients who received ozone therapy for critical stage 3 COVID patients recovered in a short time and were discharged. After this result, ozone therapy started to be applied to the patients in 17 hospitals, and 5 of the 5 patients who were intubated in the intensive care unit and connected to the respirator were extubated after ozone therapy, left the ventilator and were sent to their homes with full recovery. Again, a full recovery was observed after ozone therapy in patients in less critical condition. Good news continues to come from Italy and Spain in recent days. Anesthesiologist Prof. to 36 intensive care patients who had respiratory distress due to COVID-19 at the Santa Maria della Misericordia university hospital in Udin, Italy. Dr. Only one patient, who was treated with ozone by De Monte, had to be connected to a respirator, and the others recovered and were discharged. Also from the University of Pavia, Italy, Prof. Marianno Franzini published the results of 11 patients, 5 of whom were intubated in the intensive care unit, and it was reported that all patients except 1 recovered. In Ibiza, Spain, many patients who received ozone therapy recovered without the need for intensive care. This study was not published but reported as news.
The incredible benefits of ozone therapy in the COVID-19 pandemic have begun to be reflected in the medical literature. Medical ozone therapy is a powerful method to oxygenate mitochondria and cells without further damage. 1- It reduces oxidative stress by acting as an antioxidant to modulate the immune response and improve blood viscosity and oxygen delivery to cells.
2- Ozone activates the production of multiple endogenous antioxidants such as superoxide dismutase, glutathione peroxidase, glutathione S-transferase, heat shock proteins and phase II enzymes of drug metabolism.
3- Ozone has direct antimicrobial effects against bacteria, fungi, parasites and viruses. By oxidizing the lipid cell wall of the virus, the fragments cause the viruses to die. (Outside of the Corona virus, there are protrusions rich in envelope proteins, cysteine and tryptophan proteins, but these cannot withstand the oxidation power of ozone and become denatured).
4- It activates leukocytes in our immune system, strengthens immunity by increasing the release of growth factors from platelets.
5- By activating lipid oxidation products, it increases circulation by causing nitric oxide release from the vessel wall, thus making it easier to transport oxygen to the tissues.
6- It causes the release of more erythrocytes from the bone marrow.
7- NAD / NADH (NAD: Nicotinamide adenine dinucleotide) It improves the mitochondrial oxygen usage by repairing the mitochondria by correcting the NAD Ratio. The ratio of NAD+ to NADH is important. Because the ratio is the cell's ATP, adenosine triphosphate - how effectively the cell can produce energy.
There are many known recommendations in the context of protection measures from COVID-19. Such as maintaining social distance, isolation, washing hands, wearing masks. Subjects that we will focus on within the scope of these measures: sterilization of the environment with ozone, sterilization with ozone for food, beverage, hand and mouth and nose hygiene, the use of ozonated water and ozonated oils.
Ozone (called trioxygen) is heavier than air, a blue gas that is an ideal disinfectant for both air and water. Hotels, health centers, doctors offices and treatment rooms are quickly disinfected and sterilized with ozone, allowing them to destroy harmful microorganisms. The use of ozone ionizers is also recommended at home. It is possible to sterilize and deodorize your current automobile with ozone gas. The waste of ozone is oxygen. Kills bacteria, viruses or fungi. To date, no microorganism has been shown to be immune to the disinfectant effect of ozone.
Ozone gas can be applied to water as well as blood in the context of treatment. It is known to powerfully kill bacteria and viruses. In the comparative test results between ozone and chlorine in terms of germ-killing power, ozone kills 4500 bacteria in 1 second, while chlorine can kill in 3500 seconds. After all, ozone has 3500 times stronger germ-killing power than chlorine. Of course, it is an important detail that ozone is not a chemical substance like chlorine, but a natural substance and its waste is oxygen. Ozonated water is widely used after dental surgery to kill germs in the mouth. To protect yourself from COVID-19, it is more effective and healthier to spray ozonated water instead of spraying chemicals on your hands. Again, snorting and gargling ozonated water can provide you with extraordinary benefits. The biggest contribution of ozonated water to you in a practical context, put your vegetables and fruits in ozonated water and wait for 5 minutes. Then you can consume it without any microbes and bad smells and regain its freshness.
It is obtained by absorbing ozone gas, especially in cold pressed olive oil for a long time (up to 15 days). Ozone can be impregnated with the oils of all herbal products. The unsaturated double bonds in olive oil are saturated by ozone gas. A very strong substance called ozonide, which is white in appearance, is formed. It is widely used especially in skin diseases, pain and allergic conditions and wound treatment. In the context of COVID, rubbing the oil that you have dripped into your hand and into your both nostrils with an ear stick will reduce the viral load. On the other hand, mixing the ozone oil by squeezing it into half a glass of water, gargling and then swallowing it is important for teeth and gums, as well as for reducing the viral load of the mucous membrane in the throat and eliminating the living space of the virus.
Ozone therapy is a legal treatment regulated by our Ministry of Health. Although many hospitals have the necessary ozone therapy equipment, it is not possible to understand why this effective and cost-effective treatment is not widely used. Our recommendation is that, for example, our minister of health, who is in a position of responsibility, should take the initiative and start using it in the treatment of COVID-19 immediately with a circular. On the other hand, many people take ozone therapy individually to strengthen immunity in the context of preventive medicine. Our aim is to contribute to the implementation of more effective, common and inexpensive treatments for Virus + patients.
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